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Summary
The Asus Zenpad 3S 10 Z500M uses a better processor Hexa-core (2x2.1 GHz & 4x1.7 GHz) than the Google Nexus 10 P8110. This is an significant difference between these models as a fast processor guarantees that this tablet is a better choice for performing multiple tasks. The Asus Zenpad 3S 10 Z500M has more RAM (4 GB) i.e. it shows better performance in comparison to the Google Nexus 10 P8110.
The Google Nexus 10 P8110 has 2K HD (2560 x 1600 pixels) screen resolution with 298 ppi pixel density which is higher compared with the Zenpad 3S 10 Z500M 2K HD (1536 x 2048 pixels) resolution with 263 ppi pixel density. Such display resolution means that this model is a good choice for reading books. If you are a photography enthusiast then the Asus Zenpad 3S 10 Z500M is a better buy for you as this model is equipped with more quality back 5-Megapixel camera.
Another pleasant bonus of the Asus Zenpad 3S 10 Z500M is a card slot which will let you to transfer files and expand internal storage easily. The Google Nexus 10 P8110 will live for a longer time without charging because it has a better battery life. The tab is equipped with 9000 mAh cell which is 3100 mAh bigger than the Zenpad 3S 10 Z500M cell. The Asus Zenpad 3S 10 Z500M weighs 430g that is 173g less compared to the weight of the Google Nexus 10 P8110.
Taking into account the above differences the Zenpad 3S 10 Z500M becomes the best choice. Check the lowest price on Amazon.